| External Jet Nebulization and Measured Ventilator Performance. |
Jayakumaran Jeyanthan, Smaldone Gerald C, Cuccia Ann D |
Respiratory care |
2024 |
During invasive ventilation, external flow jet nebulization results in increases in displayed exhaled tidal volumes (V<sub>T</sub>). We hypothesized that the magnitude of the increase is inaccurate. A |
Ann Cuccia
|
38744474 |
PubMed |
administration
aerosols
drug delivery
drug therapy
inhalation
jet nebulizer
mechanical
mechanical ventilation
nebulizers and vaporizers
ventilators
|
| Multidrug Aerosol Delivery During Mechanical Ventilation. |
Cuccia Ann D, McPeck Michael, Lee Janice A, Smaldone Gerald C |
Journal of aerosol medicine and pulmonary drug delivery |
2023 |
<b><i>Background:</i></b> In the critically ill, pulmonary vasodilators are often provided off label to intubated patients using continuous nebulization. If additional aerosol therapies such as bronch |
Ann Cuccia
|
37256713 |
PubMed |
administration
aerosols
drug delivery
inhalation
mechanical
nebulizers and vaporizers
ventilators
|
| Real-Time Analysis of Dry-Side Nebulization With Heated Wire Humidification During Mechanical Ventilation. |
Lee Janice A, McPeck Michael, Cuccia Ann D, Smaldone Gerald C |
Respiratory care |
2022 |
Recent observational studies of nebulizers placed on the wet side of the humidifier suggest that, after some time, considerable condensation can form, which triggers an occlusion alarm. In the current |
Ann Cuccia
|
35640996 |
PubMed |
aerosol delivery
continuous drug delivery
inhalation administration
mechanical ventilation
|
| Real-Time <i>In Vitro</i> Assessment of Aerosol Delivery During Mechanical Ventilation. |
McPeck Michael, Lee Janice A, Cuccia Ann D, Smaldone Gerald C |
Journal of aerosol medicine and pulmonary drug delivery |
2022 |
<b><i>Background:</i></b> A new real-time method for assessing factors determining aerosol delivery is described. <b><i>Methods:</i></b> A breath-enhanced jet nebulizer operated in a ventilator/heated |
Ann Cuccia
|
34227873 |
PubMed |
continuous drug delivery
inhalation administration
mechanical ventilators
|
| Factors Determining Continuous Infusion Aerosol Delivery During Mechanical Ventilation. |
McPeck Michael, Ashraf Sunya, Cuccia Ann D, Smaldone Gerald C |
Respiratory care |
2021 |
Continuous nebulization of prostacyclins and albuterol by infusion pump during mechanical ventilation evolved as a popular off-label treatment for severe hypoxemic respiratory failure and asthma. Most |
Ann Cuccia
|
32967932 |
PubMed |
aerosols
bias flow
drug delivery
epoprostenol
humidifiers
inhalation administration
mechanical ventilators
nebulizers and vaporizers
|
| Face Mask Leak Determines Aerosol Delivery in Noninvasive Ventilation. |
Haw Alexandra, McPeck Michael, Cuccia Ann D, Smaldone Gerald C |
Respiratory care |
2021 |
Aerosol transport during noninvasive ventilation follows the flow of pressurized gas through the noninvasive ventilation circuit, vented via leak port and face mask, and inhaled by the patient. Recomm |
Ann Cuccia
|
32934098 |
PubMed |
administration
aerosols
drug delivery
humidifiers
inhalation
nebulizers and vaporizers
noninvasive ventilator
|
| Comparison of Vibrating Mesh, Jet, and Breath-Enhanced Nebulizers During Mechanical Ventilation. |
Ashraf Sunya, McPeck Michael, Cuccia Ann D, Smaldone Gerald C |
Respiratory care |
2020 |
This study compared 3 nebulizer technologies for inter- and intradevice reproducibility, humidification, and fill volume sensitivity during mechanical ventilation: a breath-enhanced jet nebulizer, a v |
Ann Cuccia
|
32694180 |
PubMed |
administration
aerosols
breath-enhanced
drug delivery
humidifiers
inhalation
mechanical
nebulizers and vaporizers
ventilators
|
| Wet-Side Breath-Enhanced Jet Nebulization: Controlling Drug Delivery During Mechanical Ventilation. |
Cuccia Ann D, Ashraf Sunya, McPeck Michael, Samuel Joshua, Smaldone Gerald C |
Respiratory care |
2020 |
The present study tested a novel nebulizer and circuit that use breath enhancement and breath actuation to minimize ventilator influences. The unique circuit design incorporates "wet-side" jet nebuliz |
Ann Cuccia
|
32209704 |
PubMed |
administration
aerosols
bias flow
drug delivery
humidifiers
inhalation
mechanical
nebulizers and vaporizers
ventilators
|
| Reliability of Vibrating Mesh Technology. |
Gowda Ashwin A, Cuccia Ann D, Smaldone Gerald C |
Respiratory care |
2017 |
For delivery of inhaled aerosols, vibrating mesh systems are more efficient than jet nebulizers are and do not require added gas flow. We assessed the reliability of a vibrating mesh nebulizer (Aeroge |
Ann Cuccia
|
28003554 |
PubMed |
aerosol
efficiency
mechanical ventilation
nebulizer
residual volume
run time
|
| In vitro delivery of aerosolized treprostinil via modern mechanical ventilation. |
Patel Rajeev B, Smaldone Gerald C, Cuccia Ann D, Strachan Paul |
Journal of aerosol medicine and pulmonary drug delivery |
2013 |
The Tyvaso Inhalation System is a hand-held nebulizer system used to administer treprostinil, an approved therapy for pulmonary arterial hypertension. Our goal was to establish an in vitro method for |
Ann Cuccia
|
23668545 |
PubMed |
|