| A Single Amino Acid Change in the Response Regulator PhoP, Acquired during Yersinia pestis Evolution, Affects PhoP Target Gene Transcription and Polymyxin B Susceptibility. |
Fukuto Hana S, Vadyvaloo Viveka, McPhee Joseph B, Poinar Hendrik N, Holmes Edward C, Bliska James B |
Journal of bacteriology |
2018 |
<i>Yersinia pestis</i>, the causative agent of plague, evolved from the closely related pathogen <i>Yersinia pseudotuberculosis</i> During its emergence, <i>Y. pestis</i> is believed to have acquired |
Hana Fukuto
|
29440252 |
PubMed |
PhoP
Yersinia pestis
evolution
transcription
|
| Effects of host cell sterol composition upon internalization of <i>Yersinia pseudotuberculosis</i> and clustered β1 integrin. |
Kim JiHyun, Fukuto Hana S, Brown Deborah A, Bliska James B, London Erwin |
The Journal of biological chemistry |
2018 |
<i>Yersinia pseudotuberculosis</i> is a foodborne pathogenic bacterium that causes acute gastrointestinal illness, but its mechanisms of infection are incompletely described. We examined how host cell |
Hana Fukuto
|
29197826 |
PubMed |
YadA
adhesins
bacterial adhesion
bacterial internalization
cholesterol
endocytosis
integrin
invasin
sterol
sterol substitution
|
| Editorial: Yersinia pestis survives in neutrophils and sends a PS to macrophages: bon appetit! |
Fukuto Hana S, Bliska James B |
Journal of leukocyte biology |
2014 |
|
Hana Fukuto
|
24586037 |
PubMed |
apoptosis
efferocytosis
human cells
phagosome
plague
|
| A transposon site hybridization screen identifies galU and wecBC as important for survival of Yersinia pestis in murine macrophages. |
Klein Kathryn A, Fukuto Hana S, Pelletier Mark, Romanov Galina, Grabenstein Jens P, Palmer Lance E, |
Journal of bacteriology |
2012 |
Yersinia pestis is able to survive and replicate within murine macrophages. However, the mechanism by which Y. pestis promotes its intracellular survival is not well understood. To identify genes that |
Hana Fukuto
|
22139502 |
PubMed |
|
| Global gene expression profiling of Yersinia pestis replicating inside macrophages reveals the roles of a putative stress-induced operon in regulating type III secretion and intracellular cell division. |
Fukuto Hana S, Svetlanov Anton, Palmer Lance E, Karzai A Wali, Bliska James B |
Infection and immunity |
2010 |
Yersinia pestis, the causative agent of plague, is a facultative intracellular pathogen. Previous studies have indicated that the ability of Y. pestis to survive inside macrophages may be critical dur |
Hana Fukuto
|
20566693 |
PubMed |
|
| Characterization of phagosome trafficking and identification of PhoP-regulated genes important for survival of Yersinia pestis in macrophages. |
Grabenstein Jens P, Fukuto Hana S, Palmer Lance E, Bliska James B |
Infection and immunity |
2006 |
The transcriptional activator PhoP is important for survival of Yersinia pestis in macrophage phagosomes. However, the phagosomes inhabited by Y. pestis have not been well characterized, and the mecha |
Hana Fukuto
|
16790745 |
PubMed |
|
| Feeding status and serotonin rapidly and reversibly modulate a Caenorhabditis elegans chemosensory circuit. |
Chao Michael Y, Komatsu Hidetoshi, Fukuto Hana S, Dionne Heather M, Hart Anne C |
Proceedings of the National Academy of Sciences of the United States of America |
2004 |
Serotonin (5-HT) modulates synaptic efficacy in the nervous system of vertebrates and invertebrates. In the nematode Caenorhabditis elegans, many behaviors are regulated by 5-HT levels, which are in t |
Hana Fukuto
|
15492222 |
PubMed |
|
| G protein-coupled receptor kinase function is essential for chemosensation in C. elegans. |
Fukuto Hana S, Ferkey Denise M, Apicella Alfonso J, Lans Hannes, Sharmeen Tahira, Chen Wei, Lefkowit |
Neuron |
2004 |
G protein-coupled receptors (GPCRs) mediate diverse signaling processes, including olfaction. G protein-coupled receptor kinases (GRKs) are important regulators of G protein signal transduction that s |
Hana Fukuto
|
15157420 |
PubMed |
|