Title Authors Source Publication Year Abstract Faculty Member PMID Link PubMed Keywords
Development of an open access, virtual bioinformatics lab for students in medical laboratory sciences. Fukuto Hana S, Viboud Gloria I American journal of clinical pathology 2024 Despite the growing importance of bioinformatics in molecular diagnostics, not all medical laboratory sciences (MLS) programs provide instruction in this field. We developed and assessed a virtual lab Gloria Viboud 38141225 PubMed bioinformatics education genomics medical laboratory sciences online teaching open educational resources virtual laboratory
Use of matrix-assisted laser desorption ionization time of flight (MALDI-TOF) to detect antibiotic resistance in bacteria: A scoping review. Viboud Gloria, Asaro Holly, Huang Michael Bailou American journal of clinical pathology 2024 Matrix-assisted laser desorption ionization time of flight (MALDI-TOF) has revolutionized clinical microbiology laboratories, enabling the identification of microorganisms in minutes. Although this ad Gloria Viboud 38040411 PubMed MALDI-TOF antimicrobial resistance scoping review
International health initiative: Development and pilot testing of a molecular diagnostics training program in Romania. Fukuto Hana S, Nelepcu Iulian I, Necula Steliana, Galli Nora E, Viboud Gloria I American journal of clinical pathology 2023 The implementation of nucleic acid testing in laboratory medicine has revolutionized clinical diagnosis. Unfortunately, incorporation of these technologies in less developed countries remains a challe Gloria Viboud 37196173 PubMed education molecular diagnostics training program
The Diverse Roles of the Global Transcriptional Regulator PhoP in the Lifecycle of <i>Yersinia pestis</i>. Fukuto Hana S, Viboud Gloria I, Vadyvaloo Viveka Pathogens (Basel, Switzerland) 2020 <i>Yersinia pestis</i>, the causative agent of plague, has a complex infectious cycle that alternates between mammalian hosts (rodents and humans) and insect vectors (fleas). Consequently, it must ada Gloria Viboud 33322274 PubMed PhoP Yersinia pestis flea insect vectors phagocytes plague transcription
Random mutagenesis identifies a C-terminal region of YopD important for Yersinia type III secretion function. Solomon Rebecca, Zhang Weibing, McCrann Grace, Bliska James B, Viboud Gloria I PloS one 2015 A common virulence mechanism among bacterial pathogens is the use of specialized secretion systems that deliver virulence proteins through a translocation channel inserted in the host cell membrane. D Gloria Viboud 25807250 PubMed
Modulation of innate immune responses by Yersinia type III secretion system translocators and effectors. Bliska James B, Wang Xiaoying, Viboud Gloria I, Brodsky Igor E Cellular microbiology 2013 The innate immune system of mammals responds to microbial infection through detection of conserved molecular determinants called 'pathogen-associated molecular patterns' (PAMPs). Pathogens use virulen Gloria Viboud 23834311 PubMed
Yersinia controls type III effector delivery into host cells by modulating Rho activity. Mejía Edison, Bliska James B, Viboud Gloria I PLoS pathogens 2008 Yersinia pseudotuberculosis binds to beta1 integrin receptors, and uses the type III secretion proteins YopB and YopD to introduce pores and to translocate Yop effectors directly into host cells. Y. p Gloria Viboud 18193942 PubMed
Comparison of YopE and YopT activities in counteracting host signalling responses to Yersinia pseudotuberculosis infection. Viboud Gloria I, Mejía Edison, Bliska James B Cellular microbiology 2006 Pathogenic Yersinia species share a type III secretion system that translocates Yop effector proteins into host cells to counteract signalling responses during infection. Two of these effectors, YopE Gloria Viboud 16922868 PubMed
Yersinia outer proteins: role in modulation of host cell signaling responses and pathogenesis. Viboud Gloria I, Bliska James B Annual review of microbiology 2005 A type III secretion system (TTSS) is encoded on a virulence plasmid that is common to three pathogenic Yersinia species: Y. enterocolitica, Y. pseudotuberculosis, and Y. pestis. Pathogenic Yersinia s Gloria Viboud 15847602 PubMed
Proinflammatory signalling stimulated by the type III translocation factor YopB is counteracted by multiple effectors in epithelial cells infected with Yersinia pseudotuberculosis. Viboud Gloria I, So Stephane Shu Kin, Ryndak Michelle B, Bliska James B Molecular microbiology 2003 Type III secretion systems are used by several pathogens to translocate effector proteins into host cells. Yersinia pseudotuberculosis delivers several Yop effectors (e.g. YopH, YopE and YopJ) to coun Gloria Viboud 12603736 PubMed
Measurement of pore formation by contact-dependent type III protein secretion systems. Viboud Gloria I, Bliska James B Methods in enzymology 2002 Gloria Viboud 12474398 PubMed
Identification of lngA, the structural gene of longus type IV pilus of enterotoxigenic Escherichia coli. Gómez-Duarte Oscar G, Ruiz-Tagle Alejandro, Gómez Diana C, Viboud Gloria I, Jarvis Karen G, Kaper Ja Microbiology (Reading, England) 1999 Human enterotoxigenic Escherichia coli (ETEC) produces a type IV pilus termed longus which is encoded on large plasmids in association with colonization factor antigens (CFAs) and enterotoxins. A plas Gloria Viboud 10439420 PubMed